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十九、菲佑宁®理论基础国际发表

菲佑宁®检测的理论基础是身体整体的活性氧动态通过 扩散在气道粘液中的过氧化氢检测进行观察和判断。该验证 已在国际国内得到大量研究证实。下面是国际学术期刊上发 表的研究论文名录。

1.Buccellato F , D'Anca M , Fenoglio C ,et al.Role of Oxidative Damage in Alzheimer 's Disease and Neurodegeneration: From

Pathogenic Mechanisms to Biomarker Discovery.[J].Antioxidants (Basel, Switzerland), 2021, 10(9).DOI:10.3390/antiox10091353.

2.Liu X , Lin J , Zhang H ,et al.Oxidative Stress in Autism Spectrum Disorder-Current Progress of Mechanisms and

Biomarkers[J].Frontiers in psychiatry, 2022,  13:813304.DOI:10.3389/fpsyt.2022.813304.

3.Lima J E B F , Moreira N C S , Sakamoto-Hojo E

T .Mechanisms underlying the pathophysiology of type 2

diabetes: From risk factors to oxidative stress, metabolic

dysfunction, and hyperglycemia[J].Mutation research. Genetic toxicology and environmental mutagenesis, 874-875:503437    [2024-02-06]. DOI:10. 1016/j.mrgentox.2021.503437.

4.Peña-Bautista, C.; Vigor, C.; Galano, J.-M.; Oger, C.; Durand, T.; Ferrer, I.; Cuevas,A.; López-Cuevas, R.; Baquero,

M.;López-Nogueroles, M.; et al. New screening approach for

Alzheimer’s disease risk assessment from urine lipid peroxidationcompounds. Sci. Rep. 2019, 9, 14244.

5.Choroma´nska, M.; Klimiuk,A.; Kostecka-Socho´n, P.; Wilczy ´nska, K.; Kwiatkowski, M.; Okuniewska, N.; Waszkiewicz,

N.;Zalewska,A.; Maciejczyk, M.Antioxidant Defence, Oxidative

Stress and Oxidative Damage in Saliva, Plasma and

Erythrocytesof Dementia Patients. Can Salivary AGE be a Marker of Dementia? Int. J. Mol. Sci. 2017, 18, 2205.

6.Johnson, E.C.B.; Dammer, E.B.; Duong, D.; Ping, L.; Zhou, M.; Yin, L.; Higginbotham, L.A.; Guajardo,A.; White, B.;

Troncoso,J.C.; et al. Large-scale proteomic analysis of

Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energymetabolism associated with microglia and

astrocyte activation. Nat. Med. 2020, 26, 769–780.

7.A. Strom, K. Kaul, J. Brüggemann, I. Ziegler, I. Rokitta, S.

Püttgen, J. Szendroedi, K. Müssig, M. Roden, D. Ziegler, Lower serum extracellular superoxide dismutase levels are associated

with polyneuropathy in recent-onset diabetes, Exp. Mol. Med. 49 (2017),

8.M.A.Abou-Seif,A.A. Youssef, Evaluation of some

biochemical changes in diabetic patients, Clin. Chim.Acta 346

(2004) 161–170, cccn.2004.03.030.

9.R. Sauriasari, R.Andrajati, Dharmeizar Azizahwati , D.A.

Saputri, R.U. Muris,A. Manfaatun, O.F.Amanda, H. Setiawan, N. Sakano, D.H. Wang, K. Ogino,Marker of lipid peroxidation

related to diabetic nephropathy in Indonesian type 2 diabetes

mellitus patients, Diabetes Res, Clin. Pract. 108 (2015) 193–200,

10.U. Çakatay, Protein oxidation parameters in type 2 diabetic    patients with good and poor glycaemic control, Diabetes Metab. 31 (2005) 551–557

11.E. Bigagli, L. Raimondi, E. Mannucci, C. Colombi, G. Bardini, C. Rotella,M. Lodovici, Lipid and protein oxidation products,

antioxidant status and vascular complications in poorly controlled type 2 diabetes, Br. J. Diabetes Vasc. Dis. 12 (2012) 33–39

12.James SJ, Rose S, Melnyk S, Jernigan S, Blossom S, Pavliv O, et al.Cellular and mitochondrial glutathione redox imbalance in

lymphoblastoid cells derived from children with autism. FASEB J. (2009) 23:2374

13.Fernández-Checa JC, Kaplowitz N, García-Ruiz C, ColellA , Miranda M, Marí M, et al. GSH transport in mitochondria:

defense against TNF-inducedoxidative stress and alcohol-induced defect.Am J Physiol. (1997) 273:G7

14. Manivasagam T,Arunadevi S, Essa MM, SaravanaBabu C, BorahA ,Thenmozhi AJ , et al. Role ofoxidative stress and

antioxidants in autism.Adv Neurobiol. (2020) 24:193–206.

15. Kałuzna-Czapli´nska J, Józwik-Pruska J. Chromatographic   and mass spectrometric techniques in studies on oxidative stress in autism. J Chromatogr B. (2016) 1019:4–14.

16. Varghese M, Keshav N, Jacot-Descombes S, Warda T,

Wicinski B, Dickstein DL, et al.Autism spectrum disorder:

neuropathology and animal models.Acta Neuropathol. (2017) 134:537–66.

17. Maria T ,Michel,Dietrich,et al.The role of oxidative stress in depressive disorders.[J].Current pharmaceutical design, 2012.

18. 李娜,周岐新.抑郁症发生与氧化应激关系研究进展[J].世界 科技研究与发

,2011,33(05):904-907.DOI:10. 16507/j.issn.1006-6055.2011.05. 048.


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